Kinetics of infection. Mice were infected intranasally with ∼104 CFU of CO92. At different times, lungs (A), spleens (B), and livers (C) were harvested. Seven CD1 mice and 10 C57BL/6 mice were used in this experiment. A solid triangle indicates that the number of CFU/g tissue was below the limit of detection, which occurred only with organs harvested and plated at 24 h. The asterisk indicates that the P value is 0.0431, as determined by a Mann-Whitney U test, for a comparison of CD1 liver data and C57BL/6 liver data at 48 h. The bars indicate median values.