TABLE 1.

Differences in inflammatory mediators in middle ear fluids as assessed by RayBiotech protein arrays^a

Cytokine	Fold induction
IL-1α	2.3 ± 0.9
IL-1β	1.8 ± 0.6
IL-6	3.4 ± 1.4
MCP-1	2.2 ± 0.7
MIP-1α	4.3 ± 2.7
TNF-α	6.2 ± 3.2

^aAnalyses on middle ear fluids were made using the C1000 array according to the manufacturer's instructions. Fold induction values were calculated as ratios of data obtained from middle ear fluids from animals infected with NTHi 86-028NP licD relative to values obtained from NTHi 86-028NP. MCP-1, monocyte chemoattractant protein 1; TNF-α, tumor necrosis factor alpha.