TABLE 2.
Growth of F. tularensis strains in C57BL/6 mice after intradermal inoculation
| Strain | Skin
|
Liver
|
Spleen
|
|||
|---|---|---|---|---|---|---|
| Day 3 | Day 5 | Day 3 | Day 5 | Day 3 | Day 5 | |
| LVSa | 6.57 ± 0.06c | 4.70 ± 0.61 | 6.02 ± 0.08 | 5.68 ± 0.59 | 6.07 ± 1.06 | 5.56 ± 0.59 |
| LVS-ΔkatGa | 5.26 ± 0.46d | 3.35 ± 0.45d | 5.09 ± 0.54d | 4.23 ± 0.19d | 4.86 ± 0.48d | 4.77 ± 0.24d |
| SCHU S4b | 6.43 ± 1.44 | 6.86 ± 0.36 | 4.27 ± 1.25 | 7.99 ± 0.82 | 5.32 ± 1.22 | 8.98 ± 0.88 |
| SCHU S4-ΔkatGb | 6.46 ± 0.96 | 5.72 ± 0.84e | 3.89 ± 0.97 | 6.30 ± 0.78e | 5.12 ± 0.81 | 7.43 ± 0.81e |
a
Inoculum of 4.9 log10 CFU.
b
Inoculum of 1.2 log10 CFU.
c
Average no. of CFU per organ ± standard deviation (n = 5).
d
P < 0.05 compared to LVS.
e
P < 0.05 compared to SCHU S4.