FIG. 2.

Normal bone marrow granulocyte development in CD97^−/− mice. Bone marrow cells were labeled with MAbs specific for mouse CD11b and Gr-1 and analyzed by flow cytometry. (A) Total granulocytes include Gr-1^hi CD11b^hi cells (mature peripheral granulocytes), Gr-1^int CD11b^int cells (mitotic progenitors of all granulocytes), and Gr-1^hi CD11b^lo cells (granulocytes at an intermediate stage of maturation). (B) The relative proportion of granulocytes at each stage of development is similar for wt and CD97^−/− mice (n = 3). Data are pooled from two separate experiments.