FIG. 4.

Dexamethasone inhibits the LPS-induced upregulation of TAP expression in cultured TECs. Cells were treated with or without dexamethasone (10⁻⁶ M) for 24 h prior to the addition of LPS (100 ng/ml) for 16 h. MALDI-TOF mass spectra of cytoplasmic extracts were obtained from untreated (A), LPS-treated (B), dexamethasone-treated (C), or dexamethasone- and LPS-treated (D) cells. Representative data from cells isolated from three separate animals are shown.