FIG. 6.

Dexamethasone and LPS alter proportions of peripheral blood and BALF neutrophils. Calves were injected with dexamethasone (0.1 mg/kg) or saline every 24 h for 6 days, and then LPS (500 μg in 10 ml PBS) was infused into a bronchus in the caudal lung lobe. Peripheral blood and BALF were sampled prior to treatment (day 0) and on days 2, 6, and 7 (24 h after LPS infusion). Percentages of neutrophils (A) and lymphocytes (B) in whole blood, the total cell count in BALF (C), and the percentage of neutrophils in BALF (D) were measured. Data represent the mean ± SEM counts from saline- or dexamethasone-treated calves (4 calves per group) on 4 separate days. Significance is based on repeated-measures ANOVA with post hoc Bonferroni (*, P < 0.05 for saline versus dexamethasone treated on each day).