TABLE 5.
Genes (n = 33) for predicted surface-associated proteins upregulated when group B Streptococcus was grown at td of 1.8 h with 12% DO compared with td of 11 h with 12% DO2a
| Function or description and TIGR locus | Putative identification | Gene | Fold increase |
|---|---|---|---|
| Cell envelope formation | |||
| SAG0288 | Phospho-N-acetylmuramoyl-pentapeptide transferase | mraY | 2.1 |
| SAG0405 | Protein of unknown function/lipoprotein, putative | 2.0 | |
| SAG0971 | Protein of unknown function/lipoprotein, putative | 1.9 | |
| SAG1410 | Glycosyl transferase, group 1 family protein | 2.2 | |
| SAG1412 | Polysaccharide biosynthesis protein | 1.9 | |
| SAG2143 | Membrane protein, putative | 2.3 | |
| Energy metabolism | |||
| SAG0764 | Phosphoglycerate mutase family protein | 2.7 | |
| SAG0823 | Glyceraldehyde-3-phosphate dehydrogenase, NADP dependent | gapN | 2.0 |
| SAG0859 | ATP synthase Fo, beta subunit | atpF | 2.1 |
| SAG0940 | 6-Phosphofructokinase | pfk | 3.0 |
| SAG0941 | Pyruvate kinase | pyk | 3.2 |
| SAG0959 | l-Lactate dehydrogenase | ldh | 3.0 |
| SAG1768 | Glyceraldehyde 3-phosphate dehydrogenase | gap | 2.0 |
| Conserved hypothetical proteins | |||
| SAG0303 | 1.9 | ||
| SAG0304 | 1.9 | ||
| SAG0785 | 2.1 | ||
| SAG0963 | 2.0 | ||
| SAG1830 | 1.9 | ||
| Protein fate | |||
| SAG0808 | Protease maturation protein, putative | 2.0 | |
| SAG1530 | Peptidyl-prolyl cis-trans isomerase, cyclophilin type | 1.8 | |
| SAG1828 | ATP-dependent Clp protease, ATP-binding subunit | 1.9 | |
| Purines, pyrimidines, nucleosides, and nucleotides | |||
| SAG0079 | Adenylate kinase | adk | 2.0 |
| Transcription | |||
| SAG0777 | ATP-dependent RNA helicase, DEAD/DEAH box family | 4.4 | |
| Transport and binding | |||
| SAG0365 | Xanthine/uracil permease family protein | 3.3 | |
| SAG0715 | Amino acid ABC transporter, permease protein | 1.8 | |
| SAG1085 | Xanthine permease | pbuX | 3.3 |
| SAG1466 | Glutamine ABC transporter, glutamine-binding protein/permease protein | glnP | 2.6 |
| SAG1732 | Glycerol uptake facilitator protein, putative | 2.2 | |
| SAG1796 | Amino acid ABC transporter, permease protein | 2.1 | |
| SAG2149 | Cobalt transport family protein | 1.8 | |
| Unknown function | |||
| SAG0021 | Protease, putative | 1.9 | |
| SAG0780 | Acyltransferase family protein | 2.2 | |
| SAG1939 | Protein of unknown function, TIGR00256 | 2.4 |
a
Genes (n = 8) whose encoded proteins were also revealed by proteomics are shown in boldface.