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Modulation of cytokine production by CT, LT-IIa, and LT-IIb. Splenic cell suspensions were cultured with 2 μg/ml of ConA for 4 days in the presence or absence of 1 μg/ml of CT, LT-IIa, or LT-IIb, at which time the levels of IL-6, IL-10, and IFN-γ secreted into the culture supernatants were measured by a multiplex cytokine assay. 
, , and , significant differences at P values of ≤0.05, ≤0.01, and ≤0.001, respectively, compared to cells stimulated with ConA alone.
