TABLE 3.
Evaluation of the quality and quantity of antibody responses in cattle immunized using live N. caninum tachyzoites or tachyzoite lysate in two different adjuvants and challenged with a fetopathic infection at 70 days of gestationa
| Group (immunization) | Sera taken 2 wk after second immunization or 6 wk after live immunization (1 SD)
|
Sera taken immediately before the challenge infection (1 SD)
|
Sera taken two wk post challenge infection (1 SD)
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| PP | Titer | AI | PP | Titer | AI | PP | Titer | AI | |
| 2 (live) | 58.8b (15.6) | 10.3d (1.0) | 34.0e (15.4) | 37.6f (7.3) | 8.2h (0.4) | 61.5j (5.7) | 77.2k (19.7) | 10.4m (0.6) | 63.6j (7.7) |
| 3 (VSA) | 61.4b,c (29.9) | 8.8d (0.5) | 34.6e (18.4) | 20.2g (10.1) | 5.0i (1.0) | 48.0j (15.0) | 105.4l (5.7) | 13.0n (1.4) | 54.6j (16.5) |
| 4 (Quil A) | 96.8c (18.3) | 9.3d (1.4) | 26.0e (6.0) | 27.6f (6.9) | 5.5i (0.8) | 50.0j (18.0) | 117.7l (16.3) | 13.0n (1.6) | 58.3j (12.3) |
a
Values sharing the same superscript letter denote values that are not significantly different from each other. Values with different superscripts are significantly different.