TABLE 1.
IgG antibody concentrations before and after vaccinationa
| Group (n) and time point | Concn of antibody to:
|
% of subjects with indicated concn of antibody to:
|
||||
|---|---|---|---|---|---|---|
| PT | FHA | PRN | PT, >6 EU/ml | FHA, >8 EU/ml | PRN, >8 EU/ml | |
| Vaccine (aP) group (49) | ||||||
| Prevaccination | 8 | 24 | 16 | 73 | 100 | 100 |
| Postvaccination (1 mo) | 40 | 419 | 438 | 100 | 100 | 100 |
| Postvaccination (1 yr) | 17 | 173 | 129 | 98 | 100 | 100 |
| Control (HAV) group (6) | ||||||
| Prevaccination | 6 | 16 | 16 | 67 | 100 | 83 |
| Postvaccination (1 mo) | 6 | 16 | 18 | 67 | 100 | 83 |
| Postvaccination (1 yr) | 14 | 15 | 18 | 100 | 100 | 83 |
a
Concentrations are given as geometric mean titers. Adults (n = 49) from the APERT subset for CMI analysis were vaccinated with a dose of an acellular pertussis vaccine.