TABLE 2.
Increases and decreases in IFN-γ and IL-5 pertussis antigen-specific-lymphocyte proliferation responsesa
| Group (n) and time point postimmunizationb | Change (n-fold) in IFN-γ response to:
|
Change (n-fold) in IL-5 response to:
|
||||
|---|---|---|---|---|---|---|
| PT | FHA | PRN | PT | FHA | PRN | |
| aP group (49) | ||||||
| 1 mo | 52.7 | 80.01 | 65.57 | 12.22 | 12.61 | 1.0 |
| 1 yr | 37.87 | 50.05 | 46.09 | 9.6 | 3.2 | 1.0 |
| Control group (6) | ||||||
| 1 mo | 0.57 | 0.76 | 0.08 | 0.09 | 1.00 | 0.1 |
| 1 yr | 0.00 | 0.00 | 7.90* | 0.02 | 1.00 | 6.54* |
a
Asterisks indicate cases in which one outlier was responsible for the high value.
b
Values at the indicated time points were compared to preimmunization values to determine the amount of change.