Figure 6. Effect of phospholipid vesicles of different composition on lysis by SLO and EqtII.
Uninfected RBCs (108 cells) were incubated with 2 HUs of EqtII or 4 HUs of post-activated SLO either alone or in the presence of phospholipid vesicles composed of PC, PC/SM or PC/cholesterol (chol) at concentrations equivalent to those in the RBCs. Cells were pelleted and the supernatants were assayed at 412 nm and compared with a control with no added lipid. The results shown represent the means±S.D. for triplicate determinations. The asterisk (*) indicates a P-value of <0.001.