Table 2. Effects of glucose and MeS on the ATP/ADP ratio in rat and mouse islets.
Values are means±S.E.M. for four independent experiments. Islets were prepared as described in Table 1. Control continued incubation in 4 mM glucose and did not change between 1 and 5 min. Control values are averages over all time points.
ATP/ADP ratio (rat) | ATP/ADP ratio (mouse) | |||||
---|---|---|---|---|---|---|
Time (min)… | 1 | 2 | 5 | 1 | 2 | 5 |
Glucose (4 mM) | 4.4±0.2 | 2.7±0.1 | ||||
Glucose (10 mM) | 6.7±0.6 | 7.1±0.4 | 8.1±0.6 | 4.5±0.2 | 5.2±0.1 | 4.8±0.3 |
MeS (10 mM) | 8.1±0.5 | 7.3±0.3 | 7.2±0.4 | 3.7±0.3 | 3.4±0.2 | 3.1±0.2 |