Figure 6. Characterization of the contribution of T4 to the G-quartet-like structure.

(A) Binding shift assays performed with both the ApT4-A' and ApT4-A'G2C aptamers in the presence of 150 mM of either NaCl or KCl, and with (+) or without (−) 100 μM T4. (B) CD spectra performed for the ApT4-A' aptamer under various conditions: no monovalent salt (□), 50 mM NaCl (●), 50 mM KCl (▲) and 100 μM T4 either alone (○) or with 50 mM NaCl (×).