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Clinically derived isolates replicate in R5-MaRBLE cells as efficiently as in PBMC. The replication kinetics of two clinical isolates, 8 and 9, were compared after inoculation into both R5-MaRBLE cells and human PBMC. (a) Replication kinetics of isolate 8. Open and closed triangles indicate kinetics in R5-MaRBLE cells and PBMC, respectively. (b) Replication kinetics of isolate 9. Open and closed circles indicate kinetics in R5-MaRBLE cells and PBMC, respectively. cpm, counts per minute.
