TABLE 2.
Methoda | No. of unique isolates | No. of clustered isolates | No. of clusters | No. of distinct types | Clustering rate (%)b |
---|---|---|---|---|---|
Spoligotyping | 56 | 98 | 16 | 72 | 53.2 |
MIRU-VNTR 12 old | 84 | 70 | 20 | 104 | 32.5 |
MIRU-VNTR 12 old + 3 ETR | 103 | 51 | 13 | 116 | 24.7 |
MIRU-VNTR 12 old + spoligotyping | 106 | 48 | 14 | 120 | 22.1 |
IS6110-RFLP | 115 | 39 | 13 | 128 | 16.9 |
Low-copy-no. isolates | 8 | 6 | 2 | 10 | NR |
High-copy-no. isolates | 107 | 33 | 11 | 118 | NR |
MIRU-VNTR 15 | 115 | 39 | 12 | 127 | 17.5 |
MIRU-VNTR 24 | 117 | 37 | 11 | 128 | 16.9 |
MIRU-VNTR 15 + spoligotyping | 120 | 34 | 11 | 131 | 14.9 |
MIRU-VNTR 24 + spoligotyping | 120 | 34 | 11 | 131 | 14.9 |
MIRU-VNTR 12 old, original set of 12 MIRU-VNTR loci as described previously (26, 27), MIRU-VNTR 12 old + 3 ETR, original set of 12 MIRU-VNTR loci plus three nonredundant exact-tandem-repeat loci (8), MIRU-VNTR 15 and 24, discriminatory subset of 15 loci and full set of 24 loci (Table 1) (24).
NR, not relevant.