TABLE 3.
Strain | Fluorescence signala for the following gene, codon, and allele:
|
|||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
dhpsb
|
dhfrc
|
pfcrtd
|
||||||||||||||||||||
436-437
|
540
|
581
|
613
|
51
|
59
|
108
|
164
|
CVMNK | SVMNT | CVIET | ||||||||||||
SA | SG | FG | AG | K | E | A | G | A | S | N | I | C | R | S | N | T | I | L | ||||
HB3 | 20,812 | 329 | 214 | ND | 10,083 | ND | 9,920 | 654 | 11,906 | 684 | 11,456 | 173 | 10,606 | 295 | 172 | 5,145 | 210 | 3,756 | 154 | 8,779 | 458 | 466 |
Dd2 | 201 | 1,217 | 9,969 | ND | 11,502 | ND | 10,363 | 833 | 577 | 13,008 | 1,511 | 4,610 | 294 | 5,666 | 864 | 12,947 | 724 | 10,567 | 535 | 150 | 662 | 14,551 |
K1 | 339 | 10,335 | 3,376 | ND | 12,468 | ND | 556 | 8,254 | 13,386 | 1,443 | ||||||||||||
3D7 | 13,984 | 405 | 9,888 | 374 | 11,162 | 1,192 | 456 | 12,879 | 553 | |||||||||||||
FCB | 13,079 | 498 | 7,921 | 265 | 1,531 | 346 | 9,572 | 10,948 | 517 | |||||||||||||
VS/1 | 1,174 | 4,813 | 159 | 4,081 | 547 | 12,575 | 444 | 617 | 2,695 | |||||||||||||
7G8 | 218 | 15,142 | 744 |
Expressed as MFI units. Boldfacing indicates positive allele-specific signals. ND, not done.
dhps haplotypes for P. falciparum strains are as follows: for HB3, SAKAA; for Dd2, FGKAS; for K1, SGKGA. No P. falciparum strain carrying the dhps 436-437 AG allele or the 540E allele was available.
dhfr haplotypes for P. falciparum strains are as follows: for HB3, NCNI; for Dd2, IRNI; for 3D7, NCSI; for FCB, NCTI; for VS/1, IRNL.
pfcrt haplotypes for P. falciparum strains are as follows: for HB3, CVMNK; for Dd2, CVIET; for 7G8, SVMNT.