TABLE 2.
Type identification of hAdV DNA detected in conjunctival swabs and eye drops used by patients with conjunctivitis by phylogenetic analysis
| Typing by phylogeny | No. of identical nucleotide sequences | No. of copies/mla
|
Highest-scoring heterologous prototype
|
Representative sample (isolate/yr) | |||||
|---|---|---|---|---|---|---|---|---|---|
| Source and virus type | Bootstrap (%) | Identity (%) | Minimum | Maximum | Mean | Type(s) | Identity (%) | ||
| Conjunctival swab | |||||||||
| AdV-3 | 88 | 99.1 | 18 | 2.0 × 105 | 2.2 × 1010 | 9.9 × 106 | AdV-7 | 97.7 | C058/2003 |
| AdV-3 | 88 | 98.9 | 4 | 1.4 × 106 | 7.6 × 107 | 2.1 × 104 | AdV-7 | 97.1 | C064/2003 |
| AdV-3 | 88 | 98.6 | 1 | 5.6 × 107 | AdV-7 | 97.7 | C082/2003 | ||
| AdV-3 | 88 | 98.9 | 1 | 9.6 × 107 | AdV-7 | 97.4 | H1009-6/2003 | ||
| AdV-4 | 100 | 96.0 | 14 | 7.0 × 104 | 5.6 × 108 | 2.7 × 107 | AdV-25, AdV-32, AdV-37, AdV-49 | 89.7 | C003/2003 |
| AdV-8 | 87 | 99.7 | 1 | 4.2 × 108 | AdV-29 | 94.6 | H1009-16/2003 | ||
| AdV-19a | 100 | 100 | 19 | 2.0 × 106 | 2.4 × 109 | 4.2 × 107 | AdV-25, AdV-26, AdV-38, AdV-49 | 97.4 | C001/2003 |
| AdV-37 | 70 | 100 | 35 | 4.8 × 102 | 2.0 × 108 | 1.3 × 106 | AdV-25 | 98.9 | C004/2003 |
| AdV-37 | 70 | 99.7 | 2 | 1.3 × 104 | 1.6 × 106 | 8.1 × 105 | AdV-25 | 98.3 | C023/2003 |
| AdV-37 | 70 | 99.7 | 1 | 3.3 × 106 | AdV-24, AdV-25 | 98.6 | C075/2003 | ||
| AdV-37 | 70 | 99.4 | 3 | 2.4 × 105 | 2.7 × 106 | 5.2 × 105 | AdV-25 | 98.3 | C095/2003 |
| Eye drops | |||||||||
| AdV-4 | 100 | 96.0 | 1 | 1.8 × 104 | AdV-25, AdV-32, AdV-37, AdV-49 | 89.7 | |||
| AdV-8 | 100 | 98.9 | 1 | 4.2 × 108 | AdV-37 | 94.6 | |||
| AdV-19a | 100 | 100 | 1 | 5.4 × 102 | AdV-25, AdV-26, AdV-38, AdV-49 | 97.4 | |||
a
For AdV-3, the range was 2.0×105 to 2.2×1010, with a mean of 1.3×107. For AdV-37, the range was 4.8×102 to 2.0×108, with a mean of 1.3×106.