TABLE 1.
Patient age (yr) | Risk factors | HIV | No. of CD4 cells/mm3 | Viral load (copies/ml) | Antiretroviral therapye | Clinical presentation | Other STI(s) | Treatment |
---|---|---|---|---|---|---|---|---|
43 | MSM, lived in United States | + | 298 | NAc | d4T, 3TC, lopinavir-ritonavir | PRb bleeding, diarrhea; colonoscopy showed multiple ulcerative rectal lesions, probable Crohn's disease | Kaposi's sarcoma | Azithromycin, doxycycline |
55 | MSM, no travel | + | 310 | <50 | Abacavir, 3TC, nevirapine | Tenesmus, rectal bleeding for 3 mo; high-resolution anoscopy showed extensive ulcer distal to dentate line | Anal warts, syphilis | Doxycycline |
54 | MSM, no travel, SOPa venues | + | 571 | <50 | Abacavir, tenofovir, atazanavir-ritonavir | PR bleeding, sweats, lethargy for 10 days; colonoscopy showed ulcerated tumor, SCCd? | Syphilis | Doxycycline |
45 | MSM, no travel, SOP venues | + | 442 | 130 | Abacavir, 3TC, nevirapine | Anal ulceration, concurrent HSV2f infection | Tertiary-stage syphilis, gonorrhea, HSV2, HCVg | Azithromycin |
SOP, sex on premises.
PR, per-rectal.
NA, not available.
SCC, squamous cell carcinoma.
d4T, stavudine; 3TC, lamivudine.
HSV2, herpes simplex virus type 2.
HCV, hepatitis C virus.