TABLE 1.
Metronidazole treatment outcome and detection of A. vaginae
| Patient no. | Gram stain outcome (score) | Clinical outcomea | A. vaginae in pretreatment clone library | Quantitative PCR result (CTb)
|
|
|---|---|---|---|---|---|
| Pretreatment | Posttreatment | ||||
| 498 | Failure (8) | Failurec | Yes | 16.2 | 14.7 |
| 499 | Failure (8) | Cure | Yes | 18.5 | 27.0 |
| 500 | Cure (0) | Failured | Yes | 17.7 | 30.2 |
| 505 | Cure (0) | Cure | No | 21.3 | 31.9 |
| 506 | Cure (0) | Cure | No | 19.7 | 34.8 |
| 507 | Cure (0) | Cure | No | 23.1 | 28.8 |
a
Cure, none of the Amsel criteria met.
b
PCR cycle at which the specimen crossed the positivity threshold. Lower values indicate higher organism concentrations.
c
Based on persistent clue cells and discharge.
d
Based on a pH of >4.7.