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. Author manuscript; available in PMC: 2008 Feb 15.
Published in final edited form as: Biochem Pharmacol. 2006 Oct 29;73(4):481–490. doi: 10.1016/j.bcp.2006.10.026

Fig. 7.

Fig. 7

Vinblastine induces mitotic arrest in the absence or presence of c-Jun overexpression. MCF7-c-Jun cells were maintained in the presence of doxycycline (top panel) or absence of doxycycline (bottom panel) for 3 d and then treated with 0.3 μM vinblastine for the times indicated. DNA content was determined by propidium iodide staining and flow cytometry as described in Materials and Methods. The proportion of cells in different phases of the cell cycle, as well as cells with sub-G1 DNA content, are shown. The results are representative of two independent experiments.