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. Author manuscript; available in PMC: 2007 Mar 21.
Published in final edited form as: Bioorg Med Chem. 2005 Sep 1;13(17):5145–5153. doi: 10.1016/j.bmc.2005.05.051

Figure 4.

Figure 4

(a) Adenovirus mediated uptake of ribonuclease α-sarcin in the presence and absence of 1 as measured by radiolabeled 35S-Met incorporation. The increase in the quantity of Ad necessary for 50% incorporation of the radiolabel suggests that peptide 1 prevents virus escape from the endosome. (b) The same assay using type A influenza in place of adenovirus leads to a similar decrease in virus-induced α-sarcin uptake. (c) Peptide mediated permeation of synthetic liposomes containing sulforhodamine-B dye by peptides 1 and 7. Peptide was added at 60 sec to a final concentration of 10 μM.