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. Author manuscript; available in PMC: 2008 Feb 1.
Published in final edited form as: Free Radic Biol Med. 2006 Nov 3;42(3):335–342. doi: 10.1016/j.freeradbiomed.2006.10.053

Figure 3. Prolonged radical species production is PPARα dependent.

Figure 3

PPARα-null and p47 phox-null mice were fed a WY-containing diet (0.05% w/w) for 3 weeks. Following POBN administration, bile was collected for 2 hours. POBN radical adducts were detected in bile using ESR. Statistical significance (p<0.05) is indicated with an asterisk as compared to the data for control diet-fed animals.