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. Author manuscript; available in PMC: 2008 Jan 1.
Published in final edited form as: J Vasc Surg. 2007 Jan;45(1):160–168. doi: 10.1016/j.jvs.2006.09.053

Figure 5. PKCδ’s inhibition of migration and proliferation can be overcome by restoring ERK1/2 activity.

Figure 5

(A) Following low-serum incubation for 48 h, incorporation of 3H-thymidine was measured in A10 SMCs infected with equal quantities of AdNull, AdPKCδ, or AdMEK (60,000 total viral particles per cell) and stimulated for 24 h with or without PDGF-BB (5 ng/ml). (B) AdNull, AdPKCδ, or AdMEK infected A10 SMCs were serum-starved for 48 h. Chemotaxis with and without PDGF-BB (5 ng/ml) was evaluated. [n=3; *, p < 0.05 as compared to AdNull control]