Table 3.
Distribution of variant allele “A” and heterozygote “GA” genotype in European American and African American participants
| Race | FVL genotype | Allele frequency? | ||||
|---|---|---|---|---|---|---|
| GG | GA | |||||
| n | % Positive | n | % Positive | ‘G’ | ‘A’ | |
| All patients | 274 | 95.1 | 14 | 4.9 | 97.57 % | 2.43 % |
| African Americans
European Americans |
147
127 |
98.7
91.4 |
2
12 |
1.3
8.6 |
99.33 %
95.68 % |
0.67 %
4.32 % |
| p-value* | χ2 = 8.34, p = 0.004 | χ2 = 8.13, p =0.004 | ||||
?
Frequency of ‘G’ allele calculated (nGA + 2nGG)/2 total-n for racial group. Frequency of ‘A’ allele calculated (1-G) No participant was homozygous for the AA genotype
*
p-values refer to significance of differences by race