Table 1.
Cell Line | Genotype | Effects of hTERT knock down |
||
---|---|---|---|---|
Proliferation | p53 | p21 | ||
HEK | Adenoviral transformed | ↓ | ↑ | ↑ |
MDA-MB-157 | p53-/- | ↓ | - | ↑ |
SKOV-3 | p53-/-; p16INK4a-/- | - | - | ↓ |
Cell Line | Genotype | Effects of hTERT knock down |
||
---|---|---|---|---|
Proliferation | p53 | p21 | ||
HEK | Adenoviral transformed | ↓ | ↑ | ↑ |
MDA-MB-157 | p53-/- | ↓ | - | ↑ |
SKOV-3 | p53-/-; p16INK4a-/- | - | - | ↓ |