Figure 2.

B-1 cell replenishment occurs in irradiated adult μ^−/− mice after adoptive cell transfer. PerC (5 × 10⁶) from C57/Igh^a donors and 3 × 10⁶ bone marrow cells from bone marrow (BM) donors were transferred into irradiated recipients as indicated. Shown are means (± SE) of total B-1 and B-2 cells recovered from groups of recipient mice (group sizes shown in Table 2) 2–3 months after cell transfer. Identification of B-1 and B-2 cells was done by FACS (Fig. 3A).