Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic Summary of Effects of Y955C Pol γ in murine model. Cardiac targeted over-expression of Y955C mutant of Pol γ results in altered mtDNA biogenesis leading to cardiac dysfunction and ultimately premature death. Demonstrated are presence of both native Pol γ and over-expressed Y955C mutants.
