Skip to main content
. Author manuscript; available in PMC: 2008 Mar 1.
Published in final edited form as: Bioorg Med Chem. 2006 Dec 13;15(5):2147–2155. doi: 10.1016/j.bmc.2006.12.016

Figure 7. Cellular processing of compound 2. Ability of intact pinealocytes to take up and process compound 2.

Figure 7

A. Zero time control. 50 μM of compound 2 incubated with intact pineal cells and immediately washed, lysed and deproteinated as described in Experimental. B. 20 min incubation of compound 2 in pinealocyte culture. The immediate product, compound 3 was detected in the cell extracts prepared from compound 2-treated pinealocyte culture. C. 60 min incubation of compound 2 in pinealocyte culture. D. control, represents the product ion profile of compound 3 in extracts of the untreated pinealocyte culture. The profiles shown are representatives of multiple experiments.