Myocyte death induced by bi-daily administration of clenbuterol.
Incidence of apoptotic (open columns) and necrotic (closed columns) myocyte death in the solei of animals that had received bi-daily subcutaneous injections of 10 μg of clenbuterol kg-1 over 32 days. No necrotic cell death was found in the soleus of animals that had received the saline vehicle only; a very low basal level (0.04 ± 0.03 %) of apoptosis was, however, detected in these muscles (data not shown). Data are expressed as means ± SEM (n = 5, in each group). * Significantly (P<0.05) different from the matched saline controls.