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. 2007 Feb 2;92(8):2964–2974. doi: 10.1529/biophysj.106.089730

FIGURE 2.

FIGURE 2

Analysis of lamellipodial protrusion in REF52 cells, adhering to (A) homogenously modified RGD surface, (B) 58-nm, and (C) 108-nm RGD nanopattern. The initial time corresponds to the first appearance of the lamellipodia in the cell (for A and B, 5–7 min after attachment; for C, 30 min). The edge displacement along the three colored lines was monitored for 160 min at 30-s intervals using kymograms. The central plots show the rate of displacement over time. The plots on the right indicate the distribution of the number of protrusion and retraction events for each sample.