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Expression of Ro1 in mouse heart causes a cardiomyopathy. (A and B) Control mouse (A, αMHC-tTA) and Ro1-expressing mouse with anasarca (B). (C and D) Photomicrographs (×5) of hematoxylin/eosin-stained cross sections of mouse heart. The ventricular chambers were larger and the ventricular walls thinner in the mouse expressing Ro1 (D) than in the control mouse (C).
