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. 2007 Mar 27;5(4):e90. doi: 10.1371/journal.pbio.0050090

Figure 2. Monitoring Genome-Wide Changes in Pre-mRNA Splicing.

Figure 2

(A) Oligos target either the pre-mRNA (P), the mature mRNA (M), or the total level of mRNA (T) for each intron-containing gene.

(B) False color representation of the splicing response of 249 different intron-containing transcripts at a single timepoint after inactivation of Prp2 activity. Each horizontal line describes the behavior of a single transcript.

(C) Time course from 0 to 30 min showing the kinetic response to inactivation of Prp2. The gene order is identical to that shown in (B).