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. 2007 Mar 7;5:13. doi: 10.1186/1479-5876-5-13

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Copyright © 2007 Intini et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Orthotopic (bone) bioassay in rats – Quantitative analysis of Tomography Data. Volume (A): only CS-Platelet, rhBMP2, and the External control showed a statistically significant difference from the negative control (p < 0.001). Surface area (B): only CS-Platelet, rhBMP2, and the External control showed a statistically significant difference from the negative control (p < 0.001). Density (C): all treatment groups showed a density of the regenerated bone statistically different from the density of the bone normally present in an area of 8 mm of the calvaria (External control)(p < 0.001).