Table 1.
JRFL gp120 | CM gp120 | IIIB gp120 | UG021 gp120 | MIP-1β | SDF-1α | |
---|---|---|---|---|---|---|
Iinward* | −474 ± 118§ | −481 ± 18¶ | −243 ± 41§ | −180 ± 46¶ | −392 ± 158 | −287 ± 70 |
Percent† | 77 | 78 | 100 | 88 | 40 | 71 |
Ioutward* | 260 ± 88 | 134 ± 46 | 384 ± 160 | 215 ± 57 | 273 ± 63 | 298 ± 59 |
Percent† | 53 | 56 | 19 | 33 | 100 | 58 |
n‡ | 17 | 9 | 16 | 22 | 20 | 24 |
I[cat] | ||||||
Percent† | 100 | 100 | 100 | 100 | 0 | 0 |
*Peak current amplitude (pA) (mean ± SEM).
†Percent of responding cells exhibiting each current.
‡ Number of responding cells examined, using cells from ≥6 donors for each ligand except UG021, which was tested in 3 donors.
§Statistically significant (P ≤ 0.05) by Student's t test.
¶Statistically significant (P ≤ 0.05) by Student's t test.