Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A). Diagram of the RHD and RHCE locus. The two RH genes have opposite orientation, with the 3′ends facing each other. Rh negative Caucasian individuals have a complete deletion of RHD. B). Rh proteins in the RBC membrane. The RhD and RhCE proteins are predicted to have twelve transmembrane domains. Amino acid positions that differ between RhD and RhCE are shown as dark circles on RhD. The amino acid changes responsible for C/c and E/e polymorphisms are shown on RhCE.
