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. 2007 Apr;13(4):573–582. doi: 10.1261/rna.407707

FIGURE 1.

FIGURE 1.

Locations and architecture of tandem TPP riboswitches. (A) TPP aptamers (encircled TPP) reside adjacent to each other in several bacteria upstream of operons usually carrying genes for TPP metabolism. (*) Lmes02000088 ORF, (**) Lmes02000087 ORF, (***) Lmes02000083 ORF. In some organisms, tenI is named thiE, and goxB is named dadA. See Fig. 2 for description of gene functions. (B) Arrangement of tandem aptamers and single expression platform (gray) of some glycine riboswitches. (Un) Stretch of repetitive U residues that is characteristic of intrinsic transcription terminators (Gusarov and Nudler 1999; Yarnell and Roberts 1999). Base-pairing portions of terminator (blue lines). (C) Tandem SAM-AdoCbl riboswitch arrangement that permits control of gene expression by two different metabolites (Sudarsan et al. 2006). (D) Arrangement of tandem TPP riboswitches.