Table 2.

Pharmacokinetic parameters of pyrimethamine in the different formulations (median value and range).

	Cmax ìmol/l	AUC24h ìmolh/l	tmax h
Formulation
Fansidar n=9	2.9 (2.0–3.9)	55 (43–69)	4 (2–6)
Homapak n=7	3.6 (2.6–4.8)	66 (54–80)	2 (2–4)
Fansidar+CQ n=8	3.3 (2.4–4.3)	63 (43–82)	4 (1–10)