Table 2.
Results of sensitivity analysis for postoperative complications
Variable | Postoperative myocardial infarction | Need for repeat revascularisation | Mortality at maximum follow-up | ||||||
---|---|---|---|---|---|---|---|---|---|
Fixed effects model | Random effects model | Fixed effects model | Random effects model | Fixed effects model | Random effects model | ||||
Overall | |||||||||
Odds ratio (95% CI) | 0.88 (0.41 to 1.88) | 0.91 (0.38 to 2.19) | 3.62 (2.38 to 5.51) | 3.66 (2.35 to 5.41) | 0.77 (0.35 to 1.71) | 0.83 (0.35 to 1.97) | |||
Heterogeneity (P value)* | 6.25 (0.40) | 3.49 (0.84) | 2.44 (0.66) | ||||||
No of adverse events†: | |||||||||
PTCS | 16/1248 | 185/1295 | 18/620 | ||||||
MIDCAB | 10/587 | 28/635 | 10/294 | ||||||
Randomised | |||||||||
Odds ratio (95% CI) | 1.36 (0.59 to 3.12) | 1.3 (0.51 to 3.32) | 4.63 (2.52 to 8.51) | 4.55 (2.47 to 8.37) | 0.57 (0.17 to 1.89) | 0.63 (0.16 to 2.40) | |||
Heterogeneity (P value)* | 4.10 (0.39) | 1.05 (0.96) | 2.14 (0.54) | ||||||
No of adverse events†: | |||||||||
PTCS | 14/378 | 57/425 | 3/179 | ||||||
MIDCAB | 9/329 | 14/377 | 6/175 | ||||||
Follow-up >12 months | |||||||||
Odds ratio (95% CI) | 0.89 (0.38 to 2.07) | 0.91 (0.29 to 2.79) | 3.7 (2.42 to 5.68) | 3.65 (2.39 to 5.59) | 0.77 (0.35 to 1.71) | 0.83 (0.35 to 1.99) | |||
Heterogeneity (P value)* | 6.24 (0.28) | 3.12 (0.79) | 2.44 (0.66) | ||||||
No of adverse events†: | |||||||||
PTCS | 12/1129 | 182/1179 | 18/620 | ||||||
MIDCAB | 8/517 | 27/567 | 10/294 | ||||||
>70 patients in each group | |||||||||
Odds ratio (95% CI) | 0.59 (0.22 to 1.55) | 0.59 (0.21 to 1.7) | 3.29 (2.08 to 5.2) | 3.24 (2.05 to 5.13) | NA | NA | |||
Heterogeneity (P value)* | 2.24 (0.52) | 2.30 (0.51) | NA | ||||||
No of adverse events†: | |||||||||
PTCS | 8/1097 | 162/1094 | NA | ||||||
MIDCAB | 8/436 | 24/434 | NA |
PTCS=percutaneous transluminal coronary artery stenting; MIDCAB=minimally invasive direct coronary artery bypass; NA=not available.
*χ2 test.
†Patients may have more than one event.