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. Author manuscript; available in PMC: 2008 Jan 1.
Published in final edited form as: Cardiovasc Res. 2006 Oct 6;73(1):48–56. doi: 10.1016/j.cardiores.2006.10.001

Fig. 5.

Fig. 5

Targeted deletion of Puma inhibits thapsigargin-induced apoptosis. Cardiomyocytes isolated from wild-type (n = 5), puma+/− (n = 4), and Puma−/− (n = 3) mice were grown in tissue culture dishes and exposed to 3 μM thapsigargin for 48 h, or left untreated. Immunoblot analysis was performed using cleaved capase 3 and Puma antibodies. Actin is shown as a loading control. Data are representative of at least three independent experiments.