Table 2.
Worst per-patient toxicity within the period of combined treatment (N = 50)
| Type of toxicity | Patients (%) | ||||
| 1 | 2 | 3 | 4 | 5 | |
| Allergy | 2 (4) | 2 (4) | 2 (4) | - | - |
| Anemia | 18 (36) | 11 (22) | 2 (4) | - | - |
| Leukopenia | - | 11 (22) | 7 (14) | 1 (2) | - |
| Neutropenia | - | 5 (10) | 13 (26) | 10 (20) | - |
| Febrile neutropenia | - | - | 4 (8) | - | - |
| Platelets | 1 (2) | 2 (4) | - | - | |
| Cardiac (LVEF decline) | 1 (2) | 2 (4) | - | - | - |
| Renal | 1 (2) | 1 (2) | - | - | 1 (2) |
| Fatigue | 12 (22) | 4 (8) | - | - | - |
| Fever | 2 (4) | 1 (2) | - | - | - |
| Hair loss | 1 (2) | - | - | - | - |
| Skin | 3 (6) | 4 (8) | - | - | - |
| Anorexia | 2 (4) | - | - | - | - |
| Constipation | 12 (24) | 3 (6) | - | - | - |
| Diarrhoea | 3 (6) | - | - | - | - |
| Nausea | 5 (10) | 2 (4) | - | - | - |
| Stomatitis | 3 (6) | - | - | - | - |
| Vomiting | 4 (8) | - | - | - | - |
| Liver | 1 (2) | 1 (2) | 1 (2) | - | - |
| Sensorial neuropathy | 4 (8) | - | - | - | - |
| Abdominal pain | 13 (26) | 1 (2) | 1 (2) | ||
| RBC transfusion | - | - | 1 (2) | - | - |
RBC = red blood cell