Table 2.
Comparison of several isolates of S. pneumoniae and their murMN mutants
| Strains | Serotype | “Clonal type” | Peptidoglycan composition | MurM gene | Penicillin MIC, μg/ml
|
|
|---|---|---|---|---|---|---|
| Intact murMN operon | Disrupted murMN operon | |||||
| R36A | — | Laboratory strain | Normal | Normal | 0.023 | 0.023 |
| 8249 | 19A | South African | Abnormal | Mosaic | 6.0 | ND |
| Pen6 | — | Transformant | Abnormal | Mosaic | 6.0 | 0.032 |
| Sp2150 | 9/14 | French/Spanish | Normal | Normal | 1.0 | 0.032 |
| Clev2 | 23F | Spanish/USA | Normal | Normal | 1.6 | 0.016 |
| Ala1 | 6B | Alaskan | Normal | Normal | 0.12 | 0.064 |
| Hun663 | 19A | Hungarian | Abnormal | Mosaic | 1.6 | ND |
| Hun663Tr4Tr5 | — | Transformant | Normal | Normal | 1.6 | 0.032 |
ND, not determined.