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X-ray diffraction patterns from human α-synuclein filaments. Wild-type α-synuclein, mutant A30P α-synuclein, mutant A53T α-synuclein, and α-synuclein (1–120) are shown. Each pattern shows a reflection at 0.47 nm. A more diffuse, weaker reflection at 1.0–1.1 nm is seen in the wild-type sample.
