Figure 3.

The effect of BIII 890 CL on veratridine-induced glutamate release and neurotoxicity in serum-free cultures of rat cortical neurons. Neurons were treated with veratridine (10 μM) for 20 min either with or without different concentrations of BIII 890 CL, the compound was washed out, and the effects of veratridine on cell viability and glutamate release were quantified 24 h later. We expressed the number of living cells in each treatment group as a percentage of healthy untreated neurons.