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. 2000 Apr 25;97(9):4956–4960. doi: 10.1073/pnas.97.9.4956

Figure 2.

Figure 2

Sequence identity among ZNT1, ZIP4, and IRT1. The deduced amino acid sequence of ZNT1 (GenBank accession no. AF133267) is aligned with the ZIP4 (GenBank accession no. U95973) and IRT1 (GenBank accession no. U27590) members of the ZIP gene family, by using the clustal method in lasergene software (DNAstar, Madison, WI). The predicted peptide encoded by ZNT1 exhibits 88% sequence identity to ZIP4 and 34% identity to IRT1; shaded areas indicate regions of identity to ZNT1. The asterisks above the sequence alignment identify the histidine-rich region located in a putative cytoplasmic domain, and the gray bars indicate the eight potential transmembrane domains predicted by tmpred (17).