Figure 2.

GR-activated transcription is not inhibited by TGF-β. Hep3B cells were transiently transfected with 0.5 μg of the reporter plasmid pGRE₄E1b-luc and 0.2 μg (A) or 2.5–40 ng of pRShGRα, as indicated (B). Cells were cultured for 24 h in the presence or absence of 50 pM TGF-β and/or 100 nM Dex. Results are presented as the mean ± SD (n = 3) of relative luciferase activity.