Abstract
Didemnins, a new class of depsipeptides isolated from a Caribbean tunicate, have been shown to have potent antiviral activity against a broad range of RNA viruses in vitro. Didemnins A and B both protected mice against a lethal challenge of Rift Valley fever virus.
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Selected References
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- Rinehart K. L., Jr, Gloer J. B., Hughes R. G., Jr, Renis H. E., McGovren J. P., Swynenberg E. B., Stringfellow D. A., Kuentzel S. L., Li L. H. Didemnins: antiviral and antitumor depsipeptides from a caribbean tunicate. Science. 1981 May 22;212(4497):933–935. doi: 10.1126/science.7233187. [DOI] [PubMed] [Google Scholar]