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Development of amphiregulin−/− mammary epithelium
| Mice | No. with no outgrowth | No. with <20% outgrowth | No. with 20–50% outgrowth | Total no. of mice |
|---|---|---|---|---|
| Virgin | 11 | 2 | 0 | 13 |
| Pregnant and postpartum | 3 | 2 | 4 | 9 |
Results of mammary gland reconstitution experiments with amphiregulin−/− mammary epithelium. Contralateral control grafts showed complete outgrowth. Different extent of outgrowth was observed depending on the developmental stage of the host.
