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. 2007 Mar;14(3):117–125. doi: 10.1101/lm.461407

Figure 4.

Figure 4.

Effects of bilateral intra-PFC injections of dopamine D1 or D2 receptor antagonist on performance in the novel object recognition test. (A,C) Exploratory preference. (B,D) Total exploration time. (A,B) SCH23390 (1 μg/0.5 μL/side) or raclopride (5 μg/0.5 μL/side) was microinjected bilaterally into the PFC of mice 15 min before the training session. The retention session was carried out 24 h (n = 7 for vehicle-treated group, n = 9 for SCH23390-treated group, n = 9 for raclopride-treated group) after the training session. (C,D) SCH23390 (1 μg/0.5 μL/side) was bilaterally microinjected into the PFC of mice 15 min before the training session. The retention session was carried out either 1 h (n = 9 for vehicle-treated group, n = 11 for SCH23390-treated group) or 24 h (n = 7 for vehicle-treated group, n = 9 for SCH23390-treated group) after the training session. Values indicate the mean ± SE. ANOVA analysis: F(2,22) = 9.915, P < 0.01 for A; F(3,32) = 15.519, P < 0.01 for C. **P < 0.01 compared to corresponding vehicle-treated group.