Figure 2. The effect of chronic icv administration of losartan on volume homeostasis in SRA mice.
Change in water intake (A), urine volume (B), and salt intake (C) in SRA mice (n = 9) and nontransgenic mice (n = 6) in response to losartan administered icv. *P = 0.007 (A); **P < 0.001 (B); #P = 0.002 (C) compared with control mice.